Biased modulators of NMDA receptors control channel opening and ion selectivity
Riley E. Perszyk, Sharon A. Swanger, Chris Shelley, Alpa Khatri, Gabriela Fernández‐Cuervo, Matthew P. Epplin, Jing Zhang, Phuong Le, Pernille Bülow, Ethel C. Garnier‐Amblard, Gangireddy PavanKumar Reddy, Gary J. Bassell, Hongjie Yuan, David S. Menaldino, Dennis C. Liotta, Lanny S. Liebeskind, Stephen F. Traynelis
Topics & Concepts
Allosteric regulationNMDA receptorChemistryAgonistIon channelBiophysicsAllosteric modulatorReceptorNeurotransmissionCalcium channelGlutamatergicIon channel linked receptorsCalciumGlutamate receptorBiochemistryBiologyAMPA receptorOrganic chemistryNeuroscience and Neuropharmacology ResearchIon channel regulation and functionReceptor Mechanisms and Signaling