Visible-Light-Promoted Intramolecular C–O Bond Formation via C<sub>sp<sup>3</sup></sub><i>–</i>H Functionalization: A Straightforward Synthetic Route to Biorelevant Dihydrofuro[3,2-<i>c</i>]chromenone Derivatives
Mullicka Mandal, Goutam Brahmachari
Abstract
A photochemical method for the synthesis of functionalized dihydrofuro[3,2-c]chromenones via intramolecular Csp3–H cross-dehydrogenative oxygenation within a warfarin framework has been unearthed. Advantages of this protocol include abundant sunlight or low-energy visible light as the energy source, mild reaction conditions, and avoidance of metal catalysts.
Topics & Concepts
Intramolecular forcePhotochemistryCatalysisChemistrySurface modificationVisible spectrumPhotocatalysisStereochemistryMaterials sciencePhysical chemistryOrganic chemistryOptoelectronicsRadical Photochemical ReactionsCatalytic C–H Functionalization MethodsOxidative Organic Chemistry Reactions