Modeling Approach to Predict the Impact of Inflammation on the Pharmacokinetics of CYP2C19 and CYP3A4 Substrates
Florian Simon, Elodie Gautier‐Veyret, Aurélie Truffot, Marylore Chenel, Léa Payen, Françoise Stanke‐Labesque, Michel Tod
Topics & Concepts
PharmacokineticsCYP3A4CYP2C19Physiologically based pharmacokinetic modellingPharmacologyOmeprazoleCytochrome P450InflammationChemistryMedicineInternal medicineMetabolismBiochemistryPharmacogenetics and Drug MetabolismEicosanoids and Hypertension PharmacologyAntiplatelet Therapy and Cardiovascular Diseases