Diagnostic criteria for mild cognitive impairment in Parkinson's disease: Movement Disorder Society Task Force guidelines
Irene Litvan, Alexander I. Tröster, Ben Schmand, Jaime Kulisevsky, Caroline H. Williams‐Gray, Roger A. Barker, Ronald C. Petersen, Jennifer G. Goldman, Dag Aarsland, Karen Marder, María Rodríguez‐Oroz, Brit Mollenhauer, Charles H. Adler, Daniel Weintraub, Murat Emre, David J. Burn
Abstract
Mild cognitive impairment is common in nondemented Parkinson’s disease (PD) patients and may be a harbinger of dementia. In view of its importance, the Movement Disorder Society commissioned a task force to delineate diagnostic criteria for mild cognitive impairment in PD. The proposed diagnostic criteria are based on a literature review and expert consensus. This article provides guidelines to characterize the clinical syndrome and methods for its diagnosis. The criteria will require validation, and possibly refinement, as additional research improves our understanding of the epidemiology, presentation, neurobiology, assessment, and long-term course of this clinical syndrome. These diagnostic criteria will support future research efforts to identify at the earliest stage those PD patients at increased risk of progressive cognitive decline and dementia who may benefit from clinical interventions at a predementia stage.