TLR4 as a therapeutic target for respiratory and neurological complications of SARS-CoV-2
Dhriti Kaushik, Ranjana Bhandari, Anurag Kuhad
Abstract
: TLR4 modulators are being investigated in clinical trials for COVID-19. Challenges in terms of structural diversity of the agents, their natural origin, and efficacy demand extensive research.
Topics & Concepts
Cytokine stormMedicineIntensive care medicineClinical trialMEDLINETLR4PandemicNatural historySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Coronavirus disease 2019 (COVID-19)ReceptorInternal medicineDiseaseBiologyInfectious disease (medical specialty)BiochemistryCOVID-19 Clinical Research StudiesLong-Term Effects of COVID-19Respiratory Support and Mechanisms