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Characterization of the acidic species of a monoclonal antibody using free flow electrophoresis fractionation and mass spectrometry

Suli Liu, Seth Madren, Pamela Feng, Zoran Sosic

2020Journal of Pharmaceutical and Biomedical Analysis28 citationsDOI

Topics & Concepts

ChemistryChromatographyDeamidationMass spectrometryIsoelectric focusingFractionationGlycationLysineCapillary electrophoresisBiochemistryAmino acidReceptorEnzymeProtein purification and stabilityAnalytical Chemistry and ChromatographyMicrofluidic and Capillary Electrophoresis Applications
Characterization of the acidic species of a monoclonal antibody using free flow electrophoresis fractionation and mass spectrometry | Litcius