Selection of healthy sperm based on positive rheotaxis using a microfluidic device
Sandhya Sharma, Md Alamgir Kabir, Waseem Asghar
Abstract
flow rate) have shown almost 100% motility, a significantly higher percentage of morphologically normal sperm cells with lesser sperm DNA fragmentation than the control (no-flow) and raw semen sample. This chip satisfies the need of a clinical setting as it is low-cost, easy to operate and uses a small semen volume for sperm sorting.
Topics & Concepts
SpermMicrofluidic chipSemenAndrologyDNA fragmentationBiologyMicrofluidicsSperm motilityAnatomyCell biologyGeneticsMaterials scienceNanotechnologyMedicineProgrammed cell deathApoptosisSperm and Testicular FunctionReproductive Biology and FertilityOvarian function and disorders