Fusion of an EGFR-antagonistic affibody enhances the anti-tumor effect of TRAIL to EGFR positive tumors
Dianlong Jia, Feifei Wang, Yue Lü, Ping Hu, Rui Wang, Guangyong Li, Renmin Liu, Jun Li, Huimin Liu, Qing Fan, Fengjiao Yuan
Topics & Concepts
Tumor necrosis factor alphaApoptosisCancer researchCytotoxicityIn vivoHoming (biology)In vitroFusion proteinEGFR inhibitorsPharmacologyEpidermal growth factor receptorChemistryMedicineReceptorImmunologyBiologyRecombinant DNABiochemistryGeneBiotechnologyEcologyMonoclonal and Polyclonal Antibodies ResearchCancer Research and TreatmentsRNA Interference and Gene Delivery