Effects of Chronic and Acute Pulmonary Hyperinflation on Phrenic Nerve Conduction in Patients with COPD
Simona Domenica Marino, Paolo Bettini, Laura Pini, Bruno Guarneri, Roberto Magri, Lara Bertolovic, Claudio Tantucci
Abstract
< 0.05). In stable COPD patients the velocity of phrenic nerve conduction was impaired mostly in the presence of pulmonary hyperinflation, while during COPD exacerbation where dynamic pulmonary hyperinflation abruptly occurs, the reversible decrease of cMAP amplitude does suggest a temporary, acute axonal damage of phrenic nerves, potentially contributing to diaphragmatic dysfunction in these circumstances.
Topics & Concepts
COPDMedicinePhrenic nerveExacerbationCardiologyDynamic hyperinflationHyperinflationAnesthesiaInternal medicineRespiratory systemLung volumesLungMonetary economicsMonetary policyEconomicsChronic Obstructive Pulmonary Disease (COPD) ResearchNeuroscience of respiration and sleepRespiratory Support and Mechanisms