Photothermal modulation of human stem cells using light-responsive 2D nanomaterials
James K. Carrow, Kanwar Abhay Singh, Manish K. Jaiswal, Adelina Ramirez, Giriraj Lokhande, Alvin T. Yeh, Tapasree Roy Sarkar, Irtisha Singh, Akhilesh K. Gaharwar
Abstract
Significance We demonstrate the ability of two-dimensional transition metal dichalcogenides (TMDs) such as molybdenum disulfide (MoS 2 ) to modulate and direct cellular functions of human stem cells through photothermal modulation. The global gene expression profile of stem cells reveals significant influence on integrins, cellular migration, and wound healing by photothermal modulation of MoS 2 . The photostimulation of MoS 2 may provide new approaches to regulate cellular migration and related functions.
Topics & Concepts
Photothermal therapyNanomaterialsModulation (music)Stem cellNanotechnologyPhotothermal effectMaterials scienceOptoelectronicsCell biologyBiologyPhysicsAcousticsNanoplatforms for cancer theranostics2D Materials and ApplicationsAdvanced biosensing and bioanalysis techniques