SIRT3-Mediated SOD2 and PGC-1α Contribute to Chemoresistance in Colorectal Cancer Cells
Masakatsu Paku, Naotsugu Haraguchi, Mitsunobu Takeda, Shiki Fujino, Takayuki Ogino, Hidekazu Takahashi, Norikatsu Miyoshi, Mamoru Uemura, T Mizushima, Hirofumi Yamamoto, Yuichiro� Doki, Hidetoshi Eguchi
Topics & Concepts
SIRT3SOD2Cancer researchOxidative stressMitochondrial ROSGene knockdownMitochondrionCancer cellSirtuinApoptosisMedicineCoactivatorReactive oxygen speciesCancerBiologySuperoxide dismutaseInternal medicineCell biologyTranscription factorBiochemistryEnzymeGeneNAD+ kinaseSirtuins and Resveratrol in MedicineMitochondrial Function and PathologyEndoplasmic Reticulum Stress and Disease