Litcius/Paper detail

Hormone-like conopeptides – new tools for pharmaceutical design

Ashlin Turner, Quentin Kaas, David J. Craik

2020RSC Medicinal Chemistry22 citationsDOIOpen Access PDF

Abstract

venom peptides and then focus on new research relating to hormone-like conopeptides and their potential applications. Finally, we briefly examine methods of chemically stabilizing conopeptides to improve their pharmacological properties. A summary is presented of conopeptides in clinical trials and a call for future work on hormone-like conopeptides.

Topics & Concepts

ConusConotoxinVenomComputational biologyChemistryBiologyBiochemistryEcologyNicotinic Acetylcholine Receptors StudyChemical Synthesis and AnalysisNeuropeptides and Animal Physiology