Loperamide induces protective autophagy and apoptosis through the ROS/JNK signaling pathway in bladder cancer
Jianjian Wu, Qiang Guo, Juntao Li, Hao Yuan, Chutian Xiao, Jianguang Qiu, Qiong Wu, Dejuan Wang, Dejuan Wang
Topics & Concepts
LoperamideAutophagyApoptosisCancer researchReactive oxygen speciesPharmacologymTORC1CancerKinaseBladder cancerCancer cellChemistryMedicinePI3K/AKT/mTOR pathwayInternal medicineBiochemistryDiarrheaAutophagy in Disease and TherapyCancer, Hypoxia, and MetabolismHeme Oxygenase-1 and Carbon Monoxide