Pt@polydopamine nanoparticles as nanozymes for enhanced photodynamic and photothermal therapy
Hongqian Cao, Yang Yang, Minghui Liang, Yuntian Ma, Nan Sun, Xibao Gao, Junbai Li
Abstract
Polydopamine nanoparticles were used to stabilize a nano-Pt catalyst to relieve tumour hypoxia in photodynamic therapy (PDT). Polydopamine not only provides a platform for carrying nano-Pt and photosensitizers but is also used as a photothermal reagent for photothermal therapy (PTT). The system presented an enhanced anti-tumor therapy effect through a combined PDT and PTT mechanism.
Topics & Concepts
Photothermal therapyPhotodynamic therapyNanotechnologyNanoparticleChemistryMaterials scienceOrganic chemistryNanoplatforms for cancer theranosticsAdvanced Nanomaterials in CatalysisAdvanced Photocatalysis Techniques