The Mystery of Rap1 Suppression of Oncogenic Ras
Ruth Nussinov, Hyunbum Jang, Mingzhen Zhang, Chung‐Jung Tsai, Anna Sablina
Topics & Concepts
Rap1Anti-apoptotic Ras signalling cascadeMAPK/ERK pathwayNanoclustersGTPaseCell biologySmall GTPaseCancer researchGTP'Guanine nucleotide exchange factorGene isoformSignal transductionPhenotypeKinaseBiologyChemistryGeneticsBiochemistryGeneOrganic chemistryEnzymeMelanoma and MAPK PathwaysProtein Kinase Regulation and GTPase SignalingCancer Mechanisms and Therapy