The Sigma-2 receptor / transmembrane protein 97 (σ2R/TMEM97) modulator JVW-1034 reduces heavy alcohol drinking and associated pain states in male mice
Sema G. Quadir, Sean M. Tanino, Christian D. Rohl, James J. Sahn, Emily J. Yao, Luiza R. Cruz, Pietro Cottone, Stephen F. Martin, Valentina Sabino
Topics & Concepts
AlcoholAlcohol use disorderEthanolReceptorNeuropathic painMedicineMotor coordinationChronic painInternal medicineAlcohol intakePharmacologyEndocrinologyChemistryBiochemistryPsychiatryPharmacological Receptor Mechanisms and EffectsNeuropeptides and Animal PhysiologyReceptor Mechanisms and Signaling