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Nanoparticles and bioorthogonal chemistry joining forces for improved biomedical applications

Javier Idiago-López, Eduardo Moreno-Antolín, Jesús M. de la Fuente, Raluca M. Fratila

2021Nanoscale Advances56 citationsDOIOpen Access PDF

Abstract

Here, we summarise the recent efforts to bring together the unique properties of nanoparticles and the remarkable features of bioorthogonal reactions to create a toolbox of new or improved biomedical applications. We show how, by joining forces, bioorthogonal chemistry and nanotechnology can overcome some of the key current limitations in the field of nanomedicine, providing better, faster and more sensitive nanoparticle-based bioimaging and biosensing techniques, as well as therapeutic nanoplatforms with superior efficacy.

Topics & Concepts

Bioorthogonal chemistryToolboxNanotechnologyNanoparticleChemistryComputer scienceClick chemistryCombinatorial chemistryMaterials scienceProgramming languageClick Chemistry and ApplicationsAdvanced biosensing and bioanalysis techniquesChemical Synthesis and Analysis
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