Prescription optimization of gastroretentive furosemide hollow-bioadhesive microspheres via Box-Behnken design: In vitro characterization and in vivo evaluation
Saige Meng, Shuangqing Wang, Ming Guan Piao
Topics & Concepts
BioadhesiveBioavailabilityMaterials scienceChromatographyDrug deliveryControlled releaseCinnarizineDifferential scanning calorimetryBox–Behnken designBiomedical engineeringChemistryNanotechnologyPharmacologyResponse surface methodologyMedicinePhysicsThermodynamicsAdvanced Drug Delivery SystemsDrug Solubulity and Delivery SystemsHydrogels: synthesis, properties, applications