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Electrochemically controlled dearomative 2,3-difunctionalization of indoles to synthesize oxoindoline derivatives

Xichao Peng, Linzi Wen, Zuozhou Ning, Zhicheng Zhang, Chengbo Sun, Yu Tang, Pengju Feng

2022Organic Chemistry Frontiers20 citationsDOI

Abstract

Electrochemistry-controlled dearomative 2,3-difunctionalization of indoles via electrochemically anode-selective oxidative cross coupling was achieved, allowing tunable access to a wide variety of synthetically useful oxindole derivatives.

Topics & Concepts

OxindoleChemistryCombinatorial chemistryAnodeElectrochemistryNanotechnologyOrganic chemistryElectrodeCatalysisPhysical chemistryMaterials scienceRadical Photochemical ReactionsCatalytic C–H Functionalization MethodsOxidative Organic Chemistry Reactions
Electrochemically controlled dearomative 2,3-difunctionalization of indoles to synthesize oxoindoline derivatives | Litcius