Direct Comparison of Four Hematopoietic Differentiation Methods from Human Induced Pluripotent Stem Cells
Melinda L. Tursky, To Ha Loi, Crisbel M. Artuz, Suad Al-Ateeq, Ernst J. Wolvetang, Helen Tao, Daniel David, Timothy J. Molloy
Abstract
progenitor cells and functional hematopoietic progenitors, while being the most time- and cost-effective and most accurately recapitulating phenotypes of Down syndrome and β-thalassemia.
Topics & Concepts
Induced pluripotent stem cellBiologyHaematopoiesisProgenitor cellStem cellCD34ImmunologyCell biologyEmbryonic stem cellGeneticsGenePluripotent Stem Cells ResearchCRISPR and Genetic EngineeringEpigenetics and DNA Methylation