Ketoacidosis in children and adolescents with newly diagnosed type 1 diabetes during the COVID-19 pandemic in Germany
Clemens Kamrath, Kirsten Mönkemöller, Torben Biester, Tilman Rohrer, Katharina Warncke, Johanna Hammersen, Reinhard W. Holl
Abstract
The authors analysed data from the German Diabetes Prospective Follow-up Registry (DPV) of children and adolescents with Type 1 diabetes (T1D) between March 13 to May 13, 2020, when most kindergartens and schools in Germany were closed due to COVID-19 restrictions. Compared to the previous 2 years, the risk of diabetic ketoacidosis (DKA) at T1D onset was nearly double during COVID-19 lockdown (adjusted relative risk: 1.84; 95% CI, 1.54-2.21) and the increased risk was highest in young children age < 6 years (2.75; 95% CI, 1.88-4.02).
Topics & Concepts
Diabetic ketoacidosisType 1 diabetesCoronavirus disease 2019 (COVID-19)MedicinePandemicPediatricsKetoacidosis2019-20 coronavirus outbreakDiabetes mellitusSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)GermanType 2 diabetesDemographyDiseaseInternal medicineEndocrinologyVirologyOutbreakInfectious disease (medical specialty)GeographyArchaeologySociologyDiabetes and associated disordersDiabetes Management and ResearchDiet, Metabolism, and Disease