Questioning the evidence behind the Saturation Model for testosterone replacement therapy in prostate cancer

Abstract

and clinical studies that were referenced as the basis when the model was presented. Despite promising associations, the evidence employed were troublingly taken out of context in many cases and applied freely in cases where it would be unwise to do so. In light of some shortcomings in evidence synthesis, we advise some caution when applying the Saturation Model in prostate cancer.

Topics & Concepts