An ultrasensitive hybridization chain reaction-amplified CRISPR-Cas12a aptasensor for extracellular vesicle surface protein quantification
Shan Xing, Zedong Lu, Qi Huang, Huilan Li, Yu Wang, Yanzhen Lai, Yi He, Min Deng, Wanli Liu
Abstract
The platform was simple and easy to operate, and this approach should be useful for the highly sensitive and versatile quantification of TEV proteins in clinical samples.
Topics & Concepts
CRISPRExtracellular vesiclesExtracellular vesicleChemistryComputational biologyMolecular biologyBiologyCell biologyMicrovesiclesGeneBiochemistrymicroRNAAdvanced biosensing and bioanalysis techniquesExtracellular vesicles in diseaseCRISPR and Genetic Engineering