Angelol-A exerts anti-metastatic and anti-angiogenic effects on human cervical carcinoma cells by modulating the phosphorylated-ERK/miR-29a-3p that targets the MMP2/VEGFA axis
Tsung‐Ho Ying, Chia‐Liang Lin, Pei‐Ni Chen, Pei‐Ju Wu, Chung‐Jung Liu, Yi‐Hsien Hsieh
Topics & Concepts
MMP2AngiogenesisChemotaxis assayMotilityMAPK/ERK pathwayVascular endothelial growth factor ACancer researchCell migrationMMP9KinaseFlow cytometryWestern blotMTT assayChemotaxisChemistryMolecular biologyBiologyCell cultureCell biologyMetastasisCell growthCancerDownregulation and upregulationVascular endothelial growth factorReceptorBiochemistryVEGF receptorsGeneticsGeneAngiogenesis and VEGF in CancerPlant chemical constituents analysisProtease and Inhibitor Mechanisms