Litcius/Paper detail

Synthesis of dihydropyrazoles enabled by Pd-catalyzed carboamination of alkenyl hydrazones with alkenyl and aryl halides

Yinqiang Wang, Shuaijie Wu, Lei Wang, Jing Sun, Chao‐Guo Yan, Ying Han

2022Organic Chemistry Frontiers18 citationsDOI

Abstract

The synthesis of dihydropyrazoles enabled by Pd-catalyzed carboamination of alkenyl hydrazones with alkenyl or aryl halides is described. This method provides a practical and efficient route towards the synthesis of functionalized dihydropyrazoles.

Topics & Concepts

ChemistryArylHalideCatalysisOrganic chemistryCombinatorial chemistryMedicinal chemistryAlkylCatalytic C–H Functionalization MethodsCatalytic Alkyne ReactionsCatalytic Cross-Coupling Reactions