Chiral sulfide and selenide catalysts for asymmetric halocyclizations and related reactions

Abstract

the formation of sulfonium ylide intermediates. Unfortunately, the types of asymmetric reactions with chiral sulfide catalysts are limited in comparison with chiral amine-catalyzed asymmetric reactions, and the development of other catalytic reactions using chiral sulfides is highly desired. Several research groups have recently discovered that newly designed chiral sulfide catalysts are quite effective for asymmetric halocyclizations. This review summarizes recent achievements in chiral sulfide-catalyzed enantioselective halocyclizations and halogenations. The asymmetric catalyses with related chiral selenides, which are used in enantioselective halogenations, are also introduced.

Topics & Concepts