Genomic Landscape of Ornithobacterium rhinotracheale in Commercial Turkey Production in the United States
Emily Smith, Elizabeth A. Miller, Bonnie Weber, Jeannette Munoz Aguayo, Cristian Flores Figueroa, Jared Huisinga, Jill Nezworski, Michelle Kromm, B. W. Wileman, Timothy J. Johnson
Abstract
The whole-genome approach enhances our understanding of evolutionary relationships between clinical Ornithobacterium rhinotracheale isolates from different commercial turkey producers and allows for identification of genes associated with virulence, antimicrobial resistance, or mobile genetic elements that are often excluded using traditional typing methods. Additionally, differentiating O. rhinotracheale isolates at the whole-genome level may provide insight into selection of the most appropriate autogenous vaccine strain, or groups of strains, for a given population of clinical isolates.