Oxymatrine attenuated isoproterenol-induced heart failure via the TLR4/NF-κB and MAPK pathways in vivo and in vitro
Haijuan Sun, Jingjing Bai, Yuting Sun, Zhen Dong, Danni Fu, Yu Wang, Cheng‐Xi Wei
Topics & Concepts
OxymatrinePharmacologyMAPK/ERK pathwayp38 mitogen-activated protein kinasesTLR4Tumor necrosis factor alphaIn vivoIκBαSophora flavescensPhosphorylationNF-κBChemistryKinaseMedicineSignal transductionInternal medicineBiologyBiochemistryBiotechnologyMatrineChromatographyBioactive natural compoundsNF-κB Signaling PathwaysCancer-related molecular mechanisms research