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Detection of Sars-Cov-2At the Point of Care

Michael J. Loeffelholz, Yi‐Wei Tang

2021Bioanalysis31 citationsDOIOpen Access PDF

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the etiologic agent of COVID-19. Testing for SARS-CoV-2 infection is a critical element of the public health response to COVID-19. Point-of-care (POC) tests can drive patient management decisions for infectious diseases, including COVID-19. POC tests are available for the diagnosis of SARS-CoV-2 infections and include those that detect SARS-CoV-2 antigens as well as amplified RNA sequences. We provide a review of SARS-CoV-2 POC tests including their performance, settings for which they might be used, their impact and future directions. Further optimization and validation, new technologies as well as studies to determine clinical and epidemiological impact of SARS-CoV-2 POC tests are needed.

Topics & Concepts

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Point-of-care testingCoronavirus disease 2019 (COVID-19)CoronavirusMedicinePoint of care2019-20 coronavirus outbreakVirologyIntensive care medicineSevere acute respiratory syndromePublic healthEpidemiologySevere acute respiratory syndrome coronavirusImmunologyPathologyInfectious disease (medical specialty)DiseaseOutbreakSARS-CoV-2 detection and testingSARS-CoV-2 and COVID-19 ResearchBiosensors and Analytical Detection
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