Gold Nanoparticles Contact with Cancer Cell: A Brief Update
Nora Bloise, Silvia Strada, Giacomo Dacarro, Livia Visai
Abstract
The fine-tuning of the physicochemical properties of gold nanoparticles has facilitated the rapid development of multifunctional gold-based nanomaterials with diagnostic, therapeutic, and therapeutic applications. Work on gold nanoparticles is increasingly focusing on their cancer application. This review provides a summary of the main biological effects exerted by gold nanoparticles on cancer cells and highlights some critical factors involved in the interaction process (protein corona, tumor microenvironment, surface functionalization). The review also contains a brief discussion of the application of gold nanoparticles in target discovery.
Topics & Concepts
Colloidal goldNanotechnologyNanoparticleSurface modificationNanomaterialsMaterials scienceCancerChemistryMedicinePhysical chemistryInternal medicineNanoparticle-Based Drug DeliveryNanoparticles: synthesis and applicationsNanoplatforms for cancer theranostics