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Single-cell RNA sequencing reveals intratumoral heterogeneity in primary uveal melanomas and identifies HES6 as a driver of the metastatic disease

Charlotte Pandiani, Thomas Strub, Nicolas Nottet, Yann Chéli, Giovanni Gambi, Karine Bille, Chrystel Husser, Mélanie Dalmasso, Guillaume E. Béranger, Sandra Lassalle, Virginie Magnone, Florence Pédeutour, Marie Irondelle, C. Maschi, Sacha Nahon‐Estève, Arnaud Martel, Jean‐Pierre Caujolle, Paul Hofman, Kévin Lebrigand, Irwin Davidson, Stéphanie Baillif, Pascal Barbry, Robert Ballotti, Corine Bertolotto

2021Cell Death and Differentiation109 citationsDOIOpen Access PDF

Topics & Concepts

MelanomaTranscriptomeMetastasisCancer researchCellBiologyDiseaseMedicineGeneCancerGene expressionPathologyGeneticsOcular Oncology and TreatmentsSingle-cell and spatial transcriptomicsImmunotherapy and Immune Responses