A cGAS-STING pathway activating cobalt(III) cyclam prodrug for combined chemotherapy and immunotherapy of breast cancer
Haiqin Song, Nicolás Montesdeoca, Elizaveta Efanova, Xuan Li, Johannes Karges, Haihua Xiao, Kun Shang, Hanchen Zhang
Topics & Concepts
ProdrugStingCyclamTumor microenvironmentImmunotherapyStimulator of interferon genesCancer researchBreast cancerPharmacologyImmune systemCancer immunotherapyCancerChemotherapyMedicineChemistryImmunologyInternal medicineInnate immune systemMetalOrganic chemistryAerospace engineeringEngineeringinterferon and immune responsesUbiquitin and proteasome pathwaysImmune Response and Inflammation