Utility of preoperative systemic inflammatory biomarkers in predicting postoperative complications after pancreaticoduodenectomy: Literature review and single center experience
Alessandro Coppola, Vincenzo La Vaccara, Lorenza Caggiati, L. Carbone, Silvia Spoto, Massimo Ciccozzi, Silvia Angeletti, Roberto Coppola, Damiano Caputo
Abstract
BACKGROUND: The role of preoperative inflammatory biomarkers (PIBs) in predicting postoperative morbidity has been assessed in colorectal and otorhinolaryngeal surgery. However, data regarding the role that preoperative inflammatory biomarkers have on morbidity after pancreaticoduodenectomiy (PD) are less consistent. AIM: To assess the utility of PIBs in predicting postoperative complications after pancreaticoduodenectomy. METHODS: -values < 0.05 were considered statistically significant. RESULTS: 0.016, PPV = 0.17, NPV = 0.98). CONCLUSION: PIBs may predict complications after PD. During postoperative care, PIB levels could influence decisions regarding the timing of drains removal and the selection of patients who might benefit from second level diagnostic exams.