PRCC-TFE3 fusion-mediated PRKN/parkin-dependent mitophagy promotes cell survival and proliferation in PRCC-TFE3 translocation renal cell carcinoma
Bo Wang, Xiaoqin Yin, Weidong Gan, Fan Pan, Shiyuan Li, Zou Xiang, Xiaodong Han, Dongmei Li
Abstract
tRCC.
Topics & Concepts
MitophagyTFE3ParkinBiologyPINK1Cell biologyFusion proteinCancer researchTranscription factorEnhancerAutophagyGeneticsApoptosisPathologyParkinson's diseaseGeneMedicineRecombinant DNADiseaseAutophagy in Disease and TherapyEndoplasmic Reticulum Stress and DiseaseEpigenetics and DNA Methylation