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Regulated control of gene therapies by drug-induced splicing

Alex Mas Monteys, Amiel A. Hundley, Paul T. Ranum, Luis Tecedor, Amy Muehlmatt, Euyn Lim, Dmitriy Lukashev, Rajeev Sivasankaran, Beverly L. Davidson

2021Nature138 citationsDOIOpen Access PDF

Topics & Concepts

GeneGene expressionInducerDrugComputational biologySmall moleculeAlternative splicingTranslation (biology)Regulation of gene expressionBiologyRNA splicingBioavailabilityDrug discoveryCell biologyPharmacologyBioinformaticsMessenger RNAGeneticsRNARNA Interference and Gene DeliveryCRISPR and Genetic EngineeringRNA and protein synthesis mechanisms
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