Revealing the impact of CD70 expression on the manufacture and functions of CAR-70 T-cells based on single-cell transcriptomics
Jiali Cheng, Yuyan Zhao, Hui Hu, Ling Tang, Yuhao Zeng, Xinyue Deng, Shengnan Ding, An‐Yuan Guo, Qing Li, Xiaojian Zhu
Topics & Concepts
Chimeric antigen receptorDegranulationBiologyT cellT-cell receptorAntigenCytotoxic T cellCancer researchCell biologyImmunologyReceptorImmune systemIn vitroGeneticsCAR-T cell therapy researchImmune Cell Function and InteractionImmunotherapy and Immune Responses