Shared molecular genetic risk of alcohol dependence and posttraumatic stress disorder (PTSD).
Christina M. Sheerin, Kaitlin E. Bountress, Jacquelyn L. Meyers, Stacey Saenz de Viteri, Hanyang Shen, Adam X. Maihofer, Laramie E. Duncan, Ananda B. Amstadter
Abstract
= .02), with sex differences identified through stratified analyses. Our results are the first to demonstrate evidence of a shared molecular genetic etiology for AD and PTSD. Further research is needed to better understand possible sex differences in shared heritability and extend these results to additional populations. (PsycInfo Database Record (c) 2020 APA, all rights reserved).
Topics & Concepts
Alcohol use disorderPsychologyTwin studyAlcohol dependencePsychiatryClinical psychologyLinkage disequilibriumPosttraumatic stressAlcoholGeneticsHeritabilityHaplotypeGeneAlleleBiologyChemistryBiochemistrySubstance Abuse Treatment and OutcomesAlcohol Consumption and Health EffectsLiver Disease Diagnosis and Treatment