Association Between Individual Air Pollution (PM<sub>10</sub>, PM<sub>2.5</sub>) Exposure and Adverse Pregnancy Outcomes in Korea: A Multicenter Prospective Cohort, Air Pollution on Pregnancy Outcome (APPO) Study
Tae Gyu Ahn, Young Ju Kim, Ga‐In Lee, Young‐Ah You, S. Kim, Rin Chae, Young Min Hur, Mi Hye Park, Jin Gon Bae, Soo-Jeong Lee, Young Han Kim, Sunghun Na
Abstract
Background: Prenatal exposure to ambient air pollution is linked to a higher risk of unfavorable pregnancy outcomes.However, the association between pregnancy complications and exposure to indoor air pollution remains unclear.The Air Pollution on Pregnancy Outcomes research is a hospital-based prospective cohort research created to look into the effects of aerodynamically exposed particulate matter (PM) 10 and PM 2.5 on pregnancy outcomes.Methods: This prospective multicenter observational cohort study was conducted from January 2021 to June 2023.A total of 662 women with singleton pregnancies enrolled in this study.An AirguardK air sensor was installed inside the homes of the participants to measure the individual PM 10 and PM 2.5 levels in the living environment.The time-activity patterns and PM 10 and PM 2.5 , determined as concentrations from the time-weighted average model, were applied to determine the anticipated exposure levels to air pollution of each pregnant woman.The relationship between air pollution exposure and pregnancy outcomes was assessed using logistic and linear regression analyses.Results: Exposure to elevated levels of PM 10 throughout the first, second, and third trimesters as well as throughout pregnancy was strongly correlated with the risk of pregnancy problems according to multiple logistic regression models adjusted for variables.Except for in the third