EZH2 has a non-catalytic and PRC2-independent role in stabilizing DDB2 to promote nucleotide excision repair
Allyson E. Koyen, Matthew Z. Madden, Dongkyoo Park, Elizabeth V. Minten, Priya Kapoor-Vazirani, Erica Werner, Neil T. Pfister, Ramona Haji‐Seyed‐Javadi, Hui Zhang, Jie Xu, Nikita Deng, Duc M. Duong, Turner Pecen, Zoë Frazier, Zachary D. Nagel, Jean‐Bernard Lazaro, Kent W. Mouw, Nicholas T. Seyfried, Carlos S. Moreno, Taofeek K. Owonikoko, Xingming Deng, David S. Yu
Topics & Concepts
EZH2PRC2BiologyCisplatinCancer researchNucleotide excision repairHistone H3DNA repairEpigeneticsGeneticsDNAChemotherapyGeneEpigenetics and DNA MethylationLung Cancer Research StudiesRNA modifications and cancer