Reprogramming tumor-associated macrophages by a dually targeted milk exosome system as a potent monotherapy for cancer
Ying Chen, Liang Gong, Yulin Cao, Zhiang Liu, Yuanben Wang, H. Li X.W. Cheng, Yuyang Feng, Surui Yao, Yuan Yin, Zhimeng Wu, Zhaohui Huang
Topics & Concepts
Cancer researchTumor microenvironmentReprogrammingExosomeImmune systemCancer immunotherapyImmunotherapyMacrophage polarizationCancerCD8Immune checkpointMicrovesiclesMedicineMacrophageIn vitroImmunologyBiologymicroRNACellInternal medicineGeneGeneticsBiochemistryImmune cells in cancerExtracellular vesicles in diseaseImmunotherapy and Immune Responses