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A single-molecule graphene quantum dot: a novel efficient photosensitizer for photodynamic cancer therapy

Jintao Chen, Shiru Yin, Futing Yang, Shengnan Guo, Jiaojiao Zhang, Zifeng Lü, Tian Gao

2025Chemical Science15 citationsDOIOpen Access PDF

Abstract

(tumor weight inhibition rate: 71%) PDT for cancer treatment. The innovative design, synthesis, and PDT application of the single-molecule HPGQD pave the way towards accelerated clinical applications of carbon nanomaterials, advancing the frontier of nanotherapeutic research.

Topics & Concepts

Photodynamic therapyPhotosensitizerQuantum dotGrapheneReactive oxygen speciesCancer therapyMoleculeIrradiationMaterials sciencePhotochemistryGraphene quantum dotNanotechnologyChemistryOptoelectronicsCancerPhysicsMedicineBiochemistryQuantum mechanicsOrganic chemistryInternal medicineCarbon and Quantum Dots ApplicationsAdvanced Nanomaterials in CatalysisGraphene and Nanomaterials Applications
A single-molecule graphene quantum dot: a novel efficient photosensitizer for photodynamic cancer therapy | Litcius