Velcrin-induced selective cleavage of tRNALeu(TAA) by SLFN12 causes cancer cell death
Sooncheol Lee, Stephanie Hoyt, Xiaoyun Wu, Colin W. Garvie, Joseph McGaunn, Mrinal Shekhar, Marcus Tötzl, Matthew G. Rees, Andrew D. Cherniack, Matthew Meyerson, Heidi Greulich
Topics & Concepts
RNase PCleavage (geology)Downregulation and upregulationCell biologyTransfer RNARibosomeChemistryProtein biosynthesisCancer cellBiologyBiochemistryRNAGeneCancerGeneticsFracture (geology)PaleontologyRNA and protein synthesis mechanismsSignaling Pathways in DiseaseAdvanced biosensing and bioanalysis techniques