Hydrogen alleviates impaired lung epithelial barrier in acute respiratory distress syndrome via inhibiting Drp1-mediated mitochondrial fission through the Trx1 pathway
Yun Long, Yang Ang, Wei Chen, Yujie Wang, Min Shi, Fan Hu, Qing-Qing Zhou, Yadan Shi, Baokui Ge, Yigen Peng, Wanyou Yu, Hongguang Bao, Qian Li, Manlin Duan, Ju Gao
Topics & Concepts
Mitochondrial fissionOccludinARDSCell biologyApoptosisOxidative stressDownregulation and upregulationReactive oxygen speciesMitochondrionTight junctionChemistryBiologyMedicineLungBiochemistryInternal medicineGeneHydrogen's biological and therapeutic effectsAnesthesia and Neurotoxicity ResearchRespiratory Support and Mechanisms