IRG1/Itaconate inhibits proliferation and promotes apoptosis of CD69+CD103+CD8+ tissue-resident memory T cells in autoimmune hepatitis by regulating the JAK3/STAT3/P53 signalling pathway
Pei Zhou, Kaixiong Tao, Liwu Zeng, Xinyu Zeng, Yaqi Wan, Gengchen Xie, Xinghua Liu, Peng Zhang
Topics & Concepts
ApoptosisCD69STAT3Cell biologyCytotoxic T cellSignalling pathwaysCD8SignallingAutoimmune hepatitisChemistryCancer researchSignal transductionBiologyImmunologyImmune systemIL-2 receptorHepatitisBiochemistryIn vitroLiver Diseases and ImmunityLiver Disease Diagnosis and TreatmentImmune Cell Function and Interaction