Inflammation of the Pleural Cavity: A Review on Pathogenesis, Diagnosis and Implications in Tumor Pathophysiology
Georgia Karpathiou, Michel Péoc’h, Anand Sundaralingam, Najib M. Rahman, Μarios E. Froudarakis
Abstract
Pleural effusions are a common respiratory condition with many etiologies. Nonmalignant etiologies explain most pleural effusions and despite being nonmalignant, they can be associated with poor survival; thus, it is important to understand their pathophysiology. Furthermore, diagnosing a benign pleural pathology always harbors the uncertainty of a false-negative diagnosis for physicians and pathologists, especially for the group of non-specific pleuritis. This review aims to present the role of the inflammation in the development of benign pleural effusions, with a special interest in their pathophysiology and their association with malignancy.
Topics & Concepts
MedicinePathophysiologyEtiologyMalignancyPathologyPathogenesisInflammationPleural effusionInternal medicinePleural and Pulmonary DiseasesOccupational and environmental lung diseasesPneumothorax, Barotrauma, Emphysema