Towards an integrative understanding of cancer mechanobiology: calcium, YAP, and microRNA under biophysical forces
Chenyu Liang, Miao Huang, Tianqi Li, Lu Li, Hayley Sussman, Yao Dai, Dietmar W. Siemann, Mingyi Xie, Xin Tang
Abstract
, YAP, and miRNAs as novel strategies for cancer mechanotheraputics. This framework has the potential to bring insights into the development of novel next-generation cancer therapies to suppress and treat tumors.
Topics & Concepts
MechanobiologymicroRNACalciumChemistryCell biologyBiologyBiochemistryOrganic chemistryGeneHippo pathway signaling and YAP/TAZCellular Mechanics and InteractionsHeat shock proteins research