Probio-X Relieves Symptoms of Hyperlipidemia by Regulating Patients’ Gut Microbiome, Blood Lipid Metabolism, and Lifestyle Habits
Huan Wang, Cuicui Ma, Yan Li, Lei Zhang, Alex Ranieri Jerônimo Lima, Chengcong Yang, Feiyan Zhao, Haifeng Han, Dongyang Shang, Fan Yang, Yuying Zhang, Heping Zhang, Zhihong Sun, Ruifang Guo
Abstract
The human gut microbiota have a potential effect on the lipid metabolism and are closely related to the disease hyperlipidemia. Our trial has demonstrated that 3-month intake of a mixed probiotic formulation alleviates hyperlipidemic symptoms, possibly by modulation of gut microbes and host lipid metabolism. The findings of the present study provide new insights into the treatment of hyperlipidemia, mechanisms of novel therapeutic strategies, and application of probiotics-based therapy.
Topics & Concepts
HyperlipidemiaLipid metabolismProbioticGut microbiomeGut floraMicrobiomeMedicineDiseaseBlood lipidsInternal medicineBiologyPhysiologyBioinformaticsCholesterolImmunologyEndocrinologyBacteriaDiabetes mellitusGeneticsGut microbiota and healthDiet and metabolism studiesProbiotics and Fermented Foods