Tofacitinib prevents depressive-like behaviors through decreased hippocampal microgliosis and increased BDNF levels in both LPS-induced and CSDS-induced mice
Yanan Gao, Kaijun Pan, Yong-Mei Zhang, Yingbei Qi, Wen-gang Chen, Ting Zhou, Hai-chao Zong, Haoran Guo, Jin-Wen Zhao, X Liu, Z A Cao, Ze Chen, Tao Yin, Yi Zang, Jia Li
Topics & Concepts
Hippocampal formationTofacitinibMedicineDentate gyrusNeuroscienceInternal medicineImmunologyPharmacologyBiologyRheumatoid arthritisTryptophan and brain disordersStress Responses and CortisolNeuroinflammation and Neurodegeneration Mechanisms