Rapid detection and quantification of paracetamol and its major metabolites using surface enhanced Raman scattering
Najla AlMasoud, Taghrid S. Alomar, Yun Xu, Cássio Lima, Royston Goodacre
Abstract
Paracetamol (acetaminophen) is an over the counter drug that is often used in suicide attempts. We have developed a SERS based assay that allows for the quantification of paracetamol and its three major metabolites.
Topics & Concepts
AcetaminophenRaman scatteringChromatographyMetaboliteDrugChemistryPharmacologyRaman spectroscopyMedicinePhysicsBiochemistryOpticsSpectroscopy Techniques in Biomedical and Chemical ResearchGold and Silver Nanoparticles Synthesis and ApplicationsProtein Interaction Studies and Fluorescence Analysis