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Abiotic reduction of ketones with silanes catalysed by carbonic anhydrase through an enzymatic zinc hydride

Pengfei Ji, Jeeyoung Park, Yang Gu, Douglas S. Clark, John F. Hartwig

2021Nature Chemistry76 citationsDOIOpen Access PDF

Topics & Concepts

ChemistrySilanesCarbonic anhydraseHydrideCatalysisZincOrganic chemistryEnzyme catalysisAbiotic componentBiocatalysisEnzymeCombinatorial chemistryReaction mechanismMetalSilanePaleontologyBiologyMetalloenzymes and iron-sulfur proteinsEnzyme function and inhibitionElectrocatalysts for Energy Conversion
Abiotic reduction of ketones with silanes catalysed by carbonic anhydrase through an enzymatic zinc hydride | Litcius